Author

Kyle J. Basham

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Geneva N. Kwaku· 2 shared Hannah E. BrowniD· 2 shared Jatin M. VyasiD· 2 shared Kirstine Nolling JenseniD· 2 shared Olivia W. HepworthiD· 2 shared Patricia SimakuiD· 2 shared Rebecca WardiD· 2 shared Adam L. HaberiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Geneva N. Kwaku

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides

Alfred T. Harding, Arianne J. Crossen, Jennifer L. Reedy, Kyle J. Basham, Olivia W. Hepworth, Yanting Zhang, Viral S. Shah, Hannah E. Brown, Manalee Vishnu Surve, Patricia Simaku, Geneva N. Kwaku, Kirstine Nolling Jensen, Yohana Otto, Rebecca Ward, George R. Thompson, , Jatin M. Vyas

This study uses single-cell RNA sequencing to analyze human airway epithelial cell responses to Aspergillus and Coccidioides, revealing distinct stress and cytokine pathways.

mBio · Oct 13, 2025Peer-reviewedImmunology

Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation

Geneva N. Kwaku, Kirstine Nolling Jensen, Patricia Simaku, Daniel J. Floyd, Joseph W. Saelens, Christopher M. Reardon, Rebecca Ward, Kyle J. Basham, Olivia W. Hepworth, Tammy D. Vyas, Daniel Zamith‐Miranda, Joshua Daniel Nosanchuk, Jatin M. Vyas, Hannah E. Brown

This study shows that fungal extracellular vesicles induce species-specific immunomodulation in macrophages through endocytosis-dependent mechanisms, with varying cytokine responses and immune signaling.

PLoS Pathogens · May 30, 2025Peer-reviewedMicrobiology