Author

Jennifer L. Reedy

Harvard UniversityORCID 0000-0002-4623-5353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Jatin M. VyasiD· 2 shared Adam L. HaberiD· 1 shared Alfred T. HardingiD· 1 shared Arianne J. CrosseniD· 1 shared Bruce S. KleiniD· 1 shared Geneva N. Kwaku· 1 shared George R. ThompsoniD· 1 shared Hannah E. BrowniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Jatin M. VyasORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Single-cell analysis of human airway epithelium identifies cell type-specific responses to Aspergillus and Coccidioides

Alfred T. Harding, Arianne J. Crossen, Jennifer L. Reedy, Kyle J. Basham, Olivia W. Hepworth, Yanting Zhang, Viral S. Shah, Hannah E. Brown, Manalee Vishnu Surve, Patricia Simaku, Geneva N. Kwaku, Kirstine Nolling Jensen, Yohana Otto, Rebecca Ward, George R. Thompson, , Jatin M. Vyas

This study uses single-cell RNA sequencing to analyze human airway epithelial cell responses to Aspergillus and Coccidioides, revealing distinct stress and cytokine pathways.

mBio · Oct 13, 2025Peer-reviewedImmunology

Blocking HXA3-mediated neutrophil elastase release during S. pneumoniae lung infection limits pulmonary epithelial barrier disruption and bacteremia

Shuying Xu, Shumin Tan, Patricia Romanos, Jennifer L. Reedy, Yihan Zhang, Michael K. Mansour, Jatin M. Vyas, Joan C. Mecsas, Hongmei Mou, John M. Leong

This study identifies HXA3 as a driver of neutrophil transmigration and elastase release during pneumococcal infection, showing that blocking these processes reduces epithelial damage and bacteremia.

mBio · Aug 9, 2024Peer-reviewedMicrobiology