Author

Kyle J. Wang

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Angelina Li· 2 shared Brian J. LeeiD· 2 shared Mauro ModestiiD· 2 shared Shan ZhaiD· 2 shared Yimeng ZhuiD· 2 shared Amandine Pelletier· 1 shared Anna‐Lena SteckelbergiD· 1 shared Antony B. HolmesiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Angelina Li

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2 papers

Recent·Most cited

Ku suppresses RNA-mediated innate immune responses in human cells to accommodate primate-specific Alu expansion.

Yimeng Zhu, Angelina Li, Suvrajit Maji, Brian J. Lee, Sophie Marianne Korn, Jake A. Gertie, Tyler J. Dorrity, Jianhua Wang, Kyle J. Wang, Amandine Pelletier, Daniel F. Moakley, Rachel D. Kelly, Antony B. Holmes, Raúl Rabadán, David R. Edgell, , Shan Zha

The paper shows Ku suppresses RNA-mediated innate immune responses in human cells, enabling primate-specific Alu element expansion by reducing dsRNA-induced inflammation.

bioRxiv · Jan 31, 2025 · PreprintGenetics

The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA

Yimeng Zhu, Brian J. Lee, 慎吾藤井, Sagun Jonchhe, Hanwen Zhang, Angelina Li, Kyle J. Wang, Eli Rothenberg, Mauro Modesti, Shan Zha

This study identifies the SAP domain of Ku70 as limiting KU lateral movement on DNA, with DNA-PKcs partially masking this function in NHEJ.

bioRxiv · Aug 26, 2024 · PreprintGenetics