Author

L. A. Chodosh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

D. Y. Grinman· 2 shared F. M. Takyar· 2 shared J. J. Wysolmerski· 2 shared J. R. Hens· 2 shared P. Dann· 2 shared A. Clemenceau· 1 shared A. Sreekumar· 1 shared B. Benz· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

D. Y. Grinman

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Author profile →

3 papers

Recent·Most cited

Cancer-Associated Hypercalcemia Signals Through the Hindbrain to cause Anorexia

D. Y. Grinman, F. M. Takyar, P. Dann, M. Shanabrough, S. Brown, A. Clemenceau, J. R. Hens, B. Stutz, L. A. Chodosh, W. Chang, G. I. Schulman, T. L. Horvath, J. J. Wysolmerski

This study shows that hypercalcemia from tumor-secreted PTHrP activates hindbrain circuits linked to anorexia, and blocking hypercalcemia prevents these effects.

bioRxiv · Mar 19, 2024 · PreprintCancer Biology

B3GALT6 Promotes Dormant Breast Cancer Cell Survival and Recurrence by Enabling Heparan Sulfate-Mediated FGF Signaling

A. Sreekumar, M. Lu, B. Choudhury, T.-c. Pan, D. K. Pant, C. J. Sterner, G. K. Belka, T. Toriumi, B. Benz, M. Escobar-Aguirre, F. E. Marino, J. D. Esko, L. A. Chodosh

The paper identifies B3GALT6 as a key regulator of dormant breast cancer cell survival and recurrence through heparan sulfate-mediated FGF signaling.

bioRxiv · Jan 31, 2023Cancer Biology

PTHrP Induces STAT5 Activation, Secretory Differentiation and Mammary Tumor Progression

D. Y. Grinman, K. Boras-Granic, F. M. Takyar, P. Dann, J. R. Hens, C. Marmol, J. Lee, J. Choi, L. A. Chodosh, M. E. Garcia Sola, J. J. Wysolmerski

This study shows PTHrP overexpression in mammary epithelial cells promotes secretory differentiation and accelerates breast tumor progression through STAT5 activation.

bioRxiv · Dec 28, 2021Cancer Biology