Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
A. Sreekumar, M. Lu, B. Choudhury, T.-c. Pan, D. K. Pant, C. J. Sterner, G. K. Belka, T. Toriumi, B. Benz, M. Escobar-Aguirre, F. E. Marino, J. D. Esko, L. A. Chodosh
The paper identifies B3GALT6 as a key regulator of dormant breast cancer cell survival and recurrence through heparan sulfate-mediated FGF signaling.
bioRxiv · Jan 31, 2023Cancer Biology
S. B. Biering, F. Tramontini Gomes de Sousa, L. V. Tjang, F. Pahmeier, R. Ruan, S. F. Blanc, T. S. Patel, C. M. Worthington, D. R. Glasner, B. Castillo-Rojas, V. Servellita, N. T. Lo, M. P. Wong, C. M. Warnes, D. R. Sandoval, , E. Harris
This study shows SARS-CoV-2 Spike protein causes barrier dysfunction and vascular leak through integrins and TGF-β signaling, independent of viral replication and ACE2.
bioRxiv · Dec 10, 2021 · PreprintMicrobiology
J. T. Sorrentino, G. J. Golden, C. Morris, C. Painter, V. Nizet, A. R. Campos, J. W. Smith, C. A. Q. Karlsson, J. Malmström, N. E. Lewis, J. D. Esko, A. Gomez Toledo
This study identifies vascular proteome changes preceding organ dysfunction in sepsis using a murine model and integrative analysis.
bioRxiv · Dec 7, 2021 · PreprintImmunology
T. M. Clausen, D. R. Sandoval, C. B. Spliid, J. Pihl, C. D. Painter, B. E. Thacker, C. A. Glass, A. Narayanan, S. A. Majowicz, Y. Zhang, J. L. Torres, G. J. Golden, R. Porell, A. F. Garretson, L. Laubach, , J. D. Esko
This study shows SARS-CoV-2 spike protein binds to heparan sulfate and ACE2 on cells codependently, forming a complex that facilitates infection, suggesting potential therapeutic targets.
Cell · Nov 1, 2020Peer-reviewedMicrobiology
C. Martino, B. P. Kellman, D. R. Sandoval, T. M. Clausen, C. A. Marotz, S. J. Song, S. Wandro, L. S. Zaramela, R. A. Salido Benitez, Q. Zhu, E. Armingol, Y. Vazquez-Baeza, D. McDonald, J. T. Sorrentino, B. Taylor, , R. Knight
This study shows that commensal bacteria modify heparan sulfate, reducing SARS-CoV-2 spike protein binding and that this bacterial presence decreases with age, increasing COVID-19 susceptibility.
bioRxiv · Aug 17, 2020 · PreprintMicrobiology