Functionally competent CD4+ T cells express high levels of T-bet in Plasmodium chabaudi infected young mice
M. R. Smith, K. GBEDANDE, C. M. Johnson, L. A. Campbell, L. B. Richard, R. S. Onjiko, N. Domingos, M. M. Opata
The paper shows that Plasmodium chabaudi infection in young mice leads to increased T-bet expression in CD4+ T cells, suggesting enhanced Th1 commitment and potential cerebral symptoms.
bioRxiv · Feb 8, 2022 · PreprintImmunology