M. M. Opata

Effects of Low-level Persistent Infection on maintenance of immunity by CD4 T cell subsets and Th1 cytokines

This study investigates how low-level persistent Plasmodium infection affects CD4 T cell subsets and Th1 cytokines, showing that it reduces Tmem survival and promotes specific effector memory cells that prolong immunity.

Functionally competent CD4+ T cells express high levels of T-bet in Plasmodium chabaudi infected young mice

The paper shows that Plasmodium chabaudi infection in young mice leads to increased T-bet expression in CD4+ T cells, suggesting enhanced Th1 commitment and potential cerebral symptoms.