Author

L. Boomaars-van der Zanden

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. H. De Wilde· 1 shared A. W. M. de Jong· 1 shared C. C. Posthuma· 1 shared E. J. Snijder· 1 shared M. Barcena· 1 shared

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2019-2019 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

A. H. De Wilde

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1 paper

Recent·Most cited

MicrobiologybioRxivMar 24, 2019

Inhibition of arterivirus RNA synthesis by cyclophilin inhibitors is counteracted by mutations in replicase transmembrane subunits

A. H. De Wilde, L. Boomaars-van der Zanden, A. W. M. de Jong…·C. C. Posthuma

This study identifies adaptive mutations in nsp2 and nsp5 of equine arteritis virus that confer resistance to cyclophilin inhibitors, revealing their role in the mechanism of action of these antiviral compounds.

DOI 10.1128/jvi.00490-19

experimental assayhost-pathogen & immune response

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