Author

L. Broggini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. Ricagno· 2 shared C. Camilloni· 1 shared C. Paissoni· 1 shared C. Pappone· 1 shared C. Visentin· 1 shared D. Erba· 1 shared E. Scalone· 1 shared F. Bacic Toplek· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

S. Ricagno

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Author profile →

2 papers

Recent·Most cited

Nanobodies counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation

L. Broggini, M. Barzago, V. Speranzini, T. Schulte, F. Sonzini, M. Giono, M. Romeo, P. Milani, S. Caminito, G. Mazzini, P. Rognoni, G. Merlini, C. Pappone, L. Anastasia, M. Nuvolone, , S. Ricagno

This study identifies nanobodies that counteract the toxicity of an amyloidogenic light chain by stabilizing a partially open dimeric conformation, revealing insights into toxicity mechanisms.

bioRxiv · Aug 28, 2023Biophysics

Multi-eGO: an in-silico lens to look into protein aggregation kinetics at atomic resolution

E. Scalone, L. Broggini, C. Visentin, D. Erba, F. Bacic Toplek, K. Peqini, S. Pellegrino, S. Ricagno, C. Paissoni, C. Camilloni

The paper introduces multi-eGO, a computational model that simulates protein aggregation kinetics at atomic resolution, showing agreement with experimental data on Transthyretin peptides.

bioRxiv · Feb 18, 2022Biochemistry