Author

K. Huard

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

I. Gutsche· 2 shared A. Burt· 1 shared A. Desfosses· 1 shared A. Fraudeau· 1 shared A.-E. Foucher· 1 shared B. Gallet· 1 shared C. K. Cassidy· 1 shared C. Liesche· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

I. Gutsche

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex

E. Dubiez, E. Pellegrini, M. Finderup Brask, W. Garland, A.-E. Foucher, K. Huard, T. H. Jensen, S. Cusack, J. Kadlec

The paper reveals how different effectors compete for binding to the CBC-ARS2 complex, influencing RNA fate through structural and biochemical analysis.

bioRxiv · Jul 25, 2023Biochemistry

The AAA+ ATPase RavA and its binding partner ViaA modulate E. coli aminoglycoside sensitivity through interaction with the inner membrane

J. Felix, L. Bumba, C. Liesche, A. Fraudeau, F. Rebeille, J. El Khoury, K. Huard, B. Gallet, C. Moriscot, J.-P. Kleman, Y. Duhoo, M. Jessop, E. Kandiah, F. Barras, J. Jouhet, I. Gutsche

This study identifies RavA and ViaA as modulators of E. coli aminoglycoside sensitivity through lipid interactions affecting membrane morphology and antibiotic resistance.

bioRxiv · Feb 6, 2022Microbiology

Complete structure of the core signalling unit of the E. coli chemosensory array in an optimised minicell strain

A. Burt, C. K. Cassidy, P. Ames, M. Bacia-Verloop, M. Baulard, K. Huard, Z. Luthey-Schulten, A. Desfosses, P. J. Stansfeld, W. Margolin, J. S. Parkinson, I. Gutsche

The paper presents a 3D map of the E. coli chemosensory core signalling unit using cryo-ET and subtomogram averaging, combined with molecular dynamics simulations to create an atomistic model.

bioRxiv · Aug 5, 2019Cell Biology