Author

L. C. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:virus· 1

Frequent Co-Authors

J. C. van Kessel· 2 shared A. Gaultier· 1 shared A. Lee· 1 shared A. R. Merchak· 1 shared B. D. Petersen· 1 shared C. A. Simpson· 1 shared C. Rivet-Noor· 1 shared D. B. Rusch· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

J. C. van Kessel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

T cell Aryl Hydrocarbon Receptor Activity Tunes the Gut Microenvironment to Sustain Autoimmunity.

A. R. Merchak, H. J. Cahill, L. C. Brown, R. M. Brown, C. Rivet-Noor, R. M. Beiter, E. R. Slogar, D. G. Olgun, A. Gaultier

This study shows that T cell AHR activity influences the gut microbiota to sustain autoimmunity in a mouse model of MS.

bioRxiv · Apr 19, 2022Immunology

Thiophenesulfonamides are specific inhibitors of quorum sensing in pathogenic Vibrios

J. D. Newman, P. Shah, J. Chopra, E. Shi, M. E. McFadden, R. E. Horness, L. C. Brown, J. C. van Kessel

The paper identifies thiophenesulfonamides as specific inhibitors of quorum sensing in Vibrio species, with PTSP showing potent activity against multiple strains.

bioRxiv · Apr 14, 2021 · PreprintMicrobiology

The quorum-sensing systems of Vibrio campbellii DS40M4 and BB120 are genetically and functionally distinct

C. A. Simpson, B. D. Petersen, N. Haas, L. Geyman, A. Lee, R. Podicheti, R. Pepin, L. C. Brown, D. B. Rusch, M. P. Manzella, K. Papenfort, J. C. van Kessel

This paper compares the quorum-sensing systems of Vibrio campbellii DS40M4 and BB120, finding genetic and functional differences in autoinducer production, regulatory mechanisms, and regulon size.

bioRxiv · Mar 31, 2020Microbiology