Author

J. D. Newman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

J. C. van Kessel· 3 shared A. B. Dalia· 1 shared A. Rapkiewicz· 1 shared A. S. Ball· 1 shared A. V. Guillen· 1 shared B. Cilhoroz· 1 shared C. A. Klancher· 1 shared C. Giannarelli· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersMicrobiology

J. C. van Kessel

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 infection triggers pro-atherogenic inflammatory 1 responses in human coronary vessels

N. Eberhardt, M. G. Noval, R. Kaur, S. Sajja, L. Amadori, D. Das, B. Cilhoroz, O. J. Stewart, D. M. Fernandez, R. Shamailova, A. V. Guillen, S. Jangra, M. Schotsaert, M. Gildea, J. D. Newman, , C. Giannarelli

This study shows SARS-CoV-2 infects macrophages in coronary atherosclerotic lesions, causing inflammation that may increase cardiovascular risk.

bioRxiv · Aug 14, 2023Immunology

Thiophenesulfonamides are specific inhibitors of quorum sensing in pathogenic Vibrios

J. D. Newman, P. Shah, J. Chopra, E. Shi, M. E. McFadden, R. E. Horness, L. C. Brown, J. C. van Kessel

The paper identifies thiophenesulfonamides as specific inhibitors of quorum sensing in Vibrio species, with PTSP showing potent activity against multiple strains.

bioRxiv · Apr 14, 2021 · PreprintMicrobiology

The DNA binding domain of the Vibrio vulnificus SmcR transcription factor is flexible and recognizes diverse DNA sequences

J. D. Newman, M. M. Russell, G. Gonzalez-Gutierrez, J. C. van Kessel

This paper investigates how SmcR, a quorum-sensing regulator in Vibrio vulnificus, recognizes diverse DNA sequences through a flexible DNA binding domain, revealing two mechanisms for transcriptional activation.

bioRxiv · Oct 30, 2020Biochemistry

Species-specific quorum sensing represses the chitobiose utilization locus in Vibrio cholerae

C. A. Klancher, J. D. Newman, A. S. Ball, J. C. van Kessel, A. B. Dalia

This study identifies HapR as a repressor of the chitobiose utilization operon in V. cholerae, showing species-specific quorum sensing regulates chitin utilization.

bioRxiv · Apr 16, 2020Microbiology