Author

L. C. Laurent

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:rat· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

G. Li· 2 shared S. Das· 2 shared A. Bagi· 1 shared A. D. Schmitt· 1 shared A. Das· 1 shared A. Khamesra· 1 shared A. M. Salvador· 1 shared A. Manning· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

G. Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Distinct stress-dependent signatures of cellular and extracellular tRNA-derived small RNAs (tDRs)

G. Li, A. Manning, A. Bagi, X. Yang, J. Howard, P. P. Chan, T. Sweeney, H. Li, B. D. Laurent, M. I. Kontaridis, L. C. Laurent, K. V. K. Jensen, S. F. Aranki, J. D. Muehlschlegel, R. Kitchen, , S. Das

The paper identifies distinct extracellular tRNA-derived small RNA (tDR) fragmentation signatures associated with different stress responses and shows their potential as biomarkers in human disease.

bioRxiv · Sep 3, 2021Cell Biology

The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

F. Boscolo Sesillo, V. Rajesh, M. Wong, P. Duran, B. Baynes, L. C. Laurent, K. Christman, A. Sacco, M. Alperin

This study shows that muscle stem cells and fibro-adipogenic progenitors are essential for pelvic floor muscle recovery after birth injury, as their loss impairs regeneration in a rat model.

bioRxiv · Jul 30, 2021Cell Biology

Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin

Y. Liu, T.-Y. Liu, D. E. Weinberg, B. W. White, C. J. De La Torre, C. L. Tan, A. D. Schmitt, S. Selvaraj, V. Tran, L. C. Laurent, L. Cabel, F.-C. Bidard, G. Putcha, I. S. Haque

The paper shows that fragment length patterns in cell-free DNA reflect in vivo chromatin organization and can identify tissues-of-origin.

bioRxiv · Oct 23, 2019 · PreprintGenomics

Red blood cell-derived extracellular vesicles mediate intercellular communication in ischemic heart failure

A. Das, N. Valkov, A. M. Salvador, I. Kur, O. Ziegler, A. Yeri, F. C. Garcia, S. Lu, A. Khamesra, C. Xiao, R. Rodosthenous, G. Li, S. Srinivasan, V. Toxavidis, J. Tigges, , S. Das

The paper uses a transgenic mouse model to show RBC-derived extracellular vesicles target cardiomyocytes and microglia in ischemic heart failure, with targeted cells showing gene enrichment in proliferation and metabolism.

bioRxiv · May 2, 2019 · PreprintCell Biology