Author

A. Sacco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Kervadec· 1 shared A. R. Colas· 1 shared B. Baynes· 1 shared C. Kwon· 1 shared C. Lee· 1 shared C.-T. Huang· 1 shared F. Boscolo Sesillo· 1 shared H. Tanaka· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Kervadec

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Author profile →

2 papers

Recent·Most cited

The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

F. Boscolo Sesillo, V. Rajesh, M. Wong, P. Duran, B. Baynes, L. C. Laurent, K. Christman, A. Sacco, M. Alperin

This study shows that muscle stem cells and fibro-adipogenic progenitors are essential for pelvic floor muscle recovery after birth injury, as their loss impairs regeneration in a rat model.

bioRxiv · Jul 30, 2021Cell Biology

Conserved Transcription Factors Control Chromatin Accessibility and Gene Expression to Maintain Cell Fate Stability and Restrict Reprogramming of Differentiated Cells

M. A. Missinato, S. A. Murphy, M. Lynott, A. Kervadec, M. S. Yu, Y.-L. Chang, S. Kannan, M. Loreti, C. Lee, P. Amatya, H. Tanaka, C.-T. Huang, P. L. Puri, C. Kwon, P. D. Adams, , A. R. Colas

This study identifies four conserved transcription factors that oppose cell fate reprogramming by controlling chromatin accessibility and gene expression, and shows their potential as therapeutic targets for regenerative medicine.

bioRxiv · Jun 28, 2021 · PreprintCell Biology