Author

C. L. Tan

Primary ORCID profile (0000-0002-2529-1030 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

C. L. TaniD3 papers · German Cancer Research Center

Biology Disciplines

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Genomics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. D. Schmitt· 1 shared A. F. Vallejo· 1 shared B. Vilaysane· 1 shared B. W. White· 1 shared C. Bai· 1 shared C. J. De La Torre· 1 shared C. L. Drum· 1 shared C. S. L. Ding· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenomics

A. D. Schmitt

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai, H. T. Chong, W. K. Teo, J. M. Hong, Q. H. Miow, P. M. Thong, B. Vilaysane, T. H. Hu, S. Chhabra, Y. Wang, S. C. Tiong, S. M. Fong, M. Kamihigashi, , C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

bioRxiv · Oct 5, 2023 · PreprintPathology

Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin

Y. Liu, T.-Y. Liu, D. E. Weinberg, B. W. White, C. J. De La Torre, C. L. Tan, A. D. Schmitt, S. Selvaraj, V. Tran, L. C. Laurent, L. Cabel, F.-C. Bidard, G. Putcha, I. S. Haque

The paper shows that fragment length patterns in cell-free DNA reflect in vivo chromatin organization and can identify tissues-of-origin.

bioRxiv · Oct 23, 2019 · PreprintGenomics