Author

M. Alperin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Organism:rat· 6 Approach:experimental assay· 5 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Boscolo Sesillo· 3 shared M. Wong· 3 shared P. Duran· 3 shared B. Baynes· 2 shared K. Christman· 2 shared K. L. Christman· 2 shared L. Burnett· 2 shared S. French· 2 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

F. Boscolo Sesillo

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Immunomodulatory Extracellular Matrix Hydrogel Mitigates Scar Formation in a Model of Tongue Fibrosis.

E. I. Zelus, A. Panduro, M. Alperin, A. M. Vahabzadeh-Hagh, K. L. Christman

This study uses a decellularized extracellular matrix hydrogel to reduce scar formation and improve muscle regeneration in a rat model of tongue fibrosis.

bioRxiv · May 17, 2022 · PreprintBioengineering

Repeated birth injuries lead to pelvic floor muscle dysfunction and impairment in regeneration

P. Duran, E. Zelus, S. French, L. Burnett, K. Christman, M. Alperin

This study shows that repeated birth injuries in rats lead to long-term pelvic floor muscle dysfunction and impaired regeneration.

bioRxiv · May 2, 2022 · PreprintPhysiology

Mechanisms governing protective pregnancy-induced adaptions of the pelvic floor muscles in the rat pre-clinical model

M. M. Rieger, M. Wong, L. A. Burnett, F. Boscolo Sesillo, B. Baynes, M. Alperin

This study investigates how mechanical load during pregnancy affects pelvic floor muscle adaptations in rats, finding that load alone can induce structural changes that partially protect against birth injury.

American Journal of Obstetrics and Gynecology · May 1, 2022Peer-reviewedPhysiology

The role of muscle stem cells and fibro-adipogenic progenitors in female pelvic floor muscle regeneration following birth injury

F. Boscolo Sesillo, V. Rajesh, M. Wong, P. Duran, B. Baynes, L. C. Laurent, K. Christman, A. Sacco, M. Alperin

This study shows that muscle stem cells and fibro-adipogenic progenitors are essential for pelvic floor muscle recovery after birth injury, as their loss impairs regeneration in a rat model.

bioRxiv · Jul 30, 2021Cell Biology

Pro-regenerative Extracellular Matrix Hydrogel Prevents and Mitigates Pathological Alterations of Pelvic Muscles Following Birth Injury

P. Duran, F. B. Sesillo, L. Burnett, S. A. Menefee, M. Cook, G. Zazueta-Damian, M. Dzieciatkowska, E. Do, S. French, M. M. Shah, C. Sanvictores, K. Hansen, M. Shtrahman, K. L. Christman, M. Alperin

This study shows that an extracellular matrix hydrogel prevents and reduces muscle atrophy and fibrosis in pelvic floor muscles after birth injury in rats.

bioRxiv · May 28, 2021 · PreprintBioengineering

Isolation of muscle stem cells from rat skeletal muscles

F. Boscolo Sesillo, M. Wong, A. Cortez, M. Alperin

This paper develops and validates a protocol for isolating muscle stem cells from rat skeletal muscles using CD106 as a marker.

bioRxiv · Jul 3, 2019Cell Biology