SARS-CoV-2 activates ER stress and Unfolded protein response
L. Rosa-Fernandes, L. C. Lazari, J. Macedo-da-Silvia, V. d. M. Gomes, R. R. G. Machado, A. F. dos Santos, D. B. Araujo, J. V. P. Coutinho, G. S. Arini, C. B. Angeli, E. E. de Souza, C. Wrenger, C. R. F. Marinho, D. B. L. Oliveira, E. L. Durigon, , G. Palmisano
This study shows SARS-CoV-2 activates ER stress and UPR pathways in infected cells, which are essential for viral replication and may be targets for antiviral drugs.
bioRxiv · Jun 21, 2021 · PreprintBiochemistry