Author

L. Castillo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Alekseyenko· 1 shared A. Bryantsev· 1 shared A. M. Law· 1 shared A. Magenau· 1 shared A. Swarbrick· 1 shared B. Elsworth· 1 shared B. Lee· 1 shared B. S. Gloss· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperPathology

A. Alekseyenko

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Author profile →

3 papers

Recent·Most cited

Quantitative model of aging-related muscle degeneration: a Drosophila study

M. Chechenova, H. Stratton, K. Kiani, E. Gerberich, A. Alekseyenko, N. Tamba, S. An, E. Czajkowski, L. Castillo, C. Talley, A. Bryantsev

This study quantifies aging-related muscle degeneration in Drosophila, showing genetic and neuronal factors contribute to muscle fiber loss.

bioRxiv · Feb 19, 2023Pathology

Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype

F. Valdes-Mora, R. Salomon, B. S. Gloss, A. M. Law, L. Castillo, K. Murphy, J. Venhuizen, A. Magenau, M. Papanicolau, L. Rodriguez de la Fuente, D. L. Roden, Y. Colino-Sanguino, Z. Kikhtyak, N. Farbehi, J. R. Conway, , D. Gallego-Ortega

The paper uses single-cell RNA sequencing to show that basal breast cancer cells mimic involution processes, involving interactions with the tumor microenvironment to promote progression.

bioRxiv · May 16, 2020Cancer Biology

MicroRNAs as potential therapeutics to enhance chemosensitivity in advancedprostate cancer

H.-M. Lin, I. Nikolic, J. Yang, L. Castillo, N. Deng, C.-L. Chan, N. K. Yeung, E. Dodson, B. Elsworth, C. Spielman, B. Lee, Z. Boyer, K. Simpson, R. J. Daly, L. G. Horvath, A. Swarbrick

This study identifies microRNA mimics that enhance taxane-induced apoptosis in CRPC cell lines, suggesting potential therapeutic use to improve chemosensitivity.

bioRxiv · Feb 28, 2018Cancer Biology