Author

D. Gallego-Ortega

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

F. Valdes-Mora· 2 shared A. Abaurrea· 1 shared A. Carracedo· 1 shared A. M. Araujo· 1 shared A. M. Law· 1 shared A. Magenau· 1 shared A. T. Dominguez· 1 shared A. Tzankov· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

F. Valdes-Mora

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3 papers

Recent·Most cited

Pleiotrophin drives a pro-metastatic immune niche within the breast tumor microenvironment

D. Ganguly, M. O. Schmidt, M. Coleman, T.-V. Ngo, N. Sorrelle, A. T. Dominguez, J. Toombs, C. Lewis, Y. Fang, F. V. Mora, D. Gallego-Ortega, A. Wellstein, R. A. Brekken

This study identifies pleiotrophin as a driver of a pro-metastatic immune niche in breast cancer, showing its role in immune suppression and metastasis, and highlights its potential as a therapeutic target.

bioRxiv · May 2, 2022Cancer Biology

Stromal Oncostatin M axis promotes breast cancer progression

A. M. Araujo, A. Abaurrea, P. Azcoaga, J. I. Lopez-Velazco, R. Rezola, I. Osorio-Querejeta, F. Valdes-Mora, J. M. Flores, L. Jenkins, P. Fernandez-Nogueira, N. Ferrari, N. Martin-Martin, A. Tzankov, S. Eppenberger-Castori, I. Alvarez-Lopez, , C. H. Lawrie

This study identifies the stromal OSM:OSMR axis as a key driver of breast cancer progression by reprogramming the tumor microenvironment.

bioRxiv · Oct 30, 2020Cancer Biology

Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype

F. Valdes-Mora, R. Salomon, B. S. Gloss, A. M. Law, L. Castillo, K. Murphy, J. Venhuizen, A. Magenau, M. Papanicolau, L. Rodriguez de la Fuente, D. L. Roden, Y. Colino-Sanguino, Z. Kikhtyak, N. Farbehi, J. R. Conway, , D. Gallego-Ortega

The paper uses single-cell RNA sequencing to show that basal breast cancer cells mimic involution processes, involving interactions with the tumor microenvironment to promote progression.

bioRxiv · May 16, 2020Cancer Biology