Author

L. Coughlin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

A. Koh· 2 shared J. Kim· 2 shared L. Hooper· 2 shared X. Zhan· 2 shared C. Behrendt· 1 shared C. Pasare· 1 shared E. Toprak· 1 shared L. Filkins· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMicrobiology

A. Koh

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2 papers

Recent·Most cited

Susceptible bacteria survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance

M. Rodrigues, P. Sabaeifard, M. S. Yildiz, L. Coughlin, S. Ahmed, C. Behrendt, X. Wang, M. Monogue, J. Kim, S. Gan, X. Zhan, L. Filkins, N. Williams, L. Hooper, A. Koh, E. Toprak

The paper shows that gut bacteria can survive antibiotic treatment without developing resistance by acquiring mutations that enhance their ability to persist and invade intestinal cells.

bioRxiv · Jan 11, 2023 · PreprintMicrobiology

Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal anti-tumor immunity

Y. Choi, Y. Gao, L. Coughlin, N. Poulides, J. Kim, X. Zhan, L. Hooper, C. Pasare, A. Koh

Immune checkpoint blockade therapy promotes gut microbiota translocation into secondary lymphoid organs, enhancing extraintestinal anti-tumor immunity.

bioRxiv · Jan 26, 2022Immunology