Author

L. Dagnino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

S. Penuela· 3 shared B. L. O'Donnell· 2 shared D. Johnston· 2 shared R. E. Sanchez-Pupo· 2 shared S. Sayedyahossein· 2 shared A. Bhatt· 1 shared A. Bysice· 1 shared C. B. Wakefield· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCancer Biology

S. Penuela

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pannexin 1 and Pannexin 3 differentially regulate the tumorigenic properties of cutaneous squamous cell carcinoma

B. L. O'Donnell, D. Johnston, A. Bhatt, Z. Kardan, D. Stefan, A. Bysice, S. Sayedyahossein, L. Dagnino, M. Cecchini, S. K. Loganathan, K. Roth, S. Penuela

This study investigates the differential roles of PANX1 and PANX3 in cutaneous squamous cell carcinoma, finding PANX1 promotes tumorigenesis while PANX3 suppresses it.

bioRxiv · Apr 8, 2024 · PreprintCancer Biology

Global Pannexin 1-deletion increases tumor-infiltrating lymphocytes in the BRAF/Pten mouse melanoma model.

R. E. Sanchez-Pupo, G. Finch, D. E. Johnston, H. Craig, R. Abdo, K. J. Barr, S. M. Kerfoot, L. Dagnino, S. Penuela

This study shows that deleting Pannexin 1 in a melanoma mouse model increases CD8+ T cell infiltration without affecting tumor growth or survival.

bioRxiv · Jul 28, 2023Cancer Biology

Pannexin 3 channels regulate architecture, adhesion, barrier function and inflammation in the skin

B. L. O'Donnell, R. E. Sanchez-Pupo, S. Sayedyahossein, M. Karimi, M. Bahmani, C. Zhang, D. Johnston, J. Kelly, C. B. Wakefield, K. Barr, L. Dagnino, S. Penuela

This study shows PANX3 is essential for maintaining skin architecture, adhesion, barrier function, and inflammation during aging, as demonstrated in knockout mice.

bioRxiv · Jul 13, 2022Cell Biology