Heat-inactivated mycobacteria activate the Toll-like receptor 2 and 4 pathways in the zebrafish model of tuberculosis
E. Ferreras Colino, M. Contreras, M. A. Risalde, I. Sevilla, E. Delgado, L. Dominguez, C. Gortazar, J. de la Fuente
The paper investigates the immune response to heat-inactivated mycobacteria in zebrafish, finding increased TLR2 and TLR4 gene expression but no reduction in mycobacterial burden.
bioRxiv · Mar 31, 2023Immunology