Author

L. Doridot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Brulport· 1 shared A. Cermolacce· 1 shared A. Lepelletier· 1 shared A. Sargsyan· 1 shared B. Raquillet· 1 shared C. Abo· 1 shared C. Berthelot· 1 shared C. Nicco· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperEvolutionary Biology

A. Brulport

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity

A. Brulport, M. A. Gazda, E. Liorzou, M. Daunesse, B. Raquillet, A. Lepelletier, M. Sopena-Rios, P. Regnard, L. Fellmann, L. Faccin, S. Garbit, A. Cermolacce, I. Kondova, M. Raliou, L. Marcellin, , C. Berthelot

The paper compares gene expression in endometrial epithelial cells across humans, mice, and non-human primates to show convergent evolution of uterine receptivity genes like LIF.

bioRxiv · Mar 13, 2024 · PreprintEvolutionary Biology

Mechanistic target of rapamycin (mTOR) regulates self-sustained quiescence, tumor indolence and late clinical metastasis in a Beclin-1-dependent manner.

C. Nicco, M. Thomas, J. Guillermet-Guibert, M. Havard, F. Laurent-Tchenio, L. Doridot, F. Dautry, F. Batteux, T. Tchenio

This study shows that mTOR regulates self-sustained quiescence in cancer cells, which contributes to tumor indolence and late metastasis through Beclin-1 dependence.

bioRxiv · May 5, 2022Cancer Biology

HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis

A. Sargsyan, L. Doridot, S. A. Hannou, W. Tong, H. Srinivasan, R. Ivison, R. Monn, H. H. Kou, J. M. Haldeman, M. Arlotto, P. J. White, P. A. Grimsrud, I. Astapova, L. Tsai, M. A. Herman

The paper identifies HGFAC as a ChREBP-regulated hepatokine that improves glucose and lipid homeostasis through activation of PPARγ in mice.

bioRxiv · Jul 29, 2021Physiology