Author

P. A. Grimsrud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sargsyan· 2 shared I. Astapova· 2 shared M. A. Herman· 2 shared S. A. Hannou· 2 shared W. Tong· 2 shared A. E. Adams· 1 shared B. J. Henriques· 1 shared C. A. Mills· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersPhysiology

A. Sargsyan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Metformin Impairs Intestinal Fructose Metabolism

W. Tong, S. A. Hannou, A. Sargsyan, G.-F. Zhang, P. A. Grimsrud, I. Astapova, M. A. Herman

This study shows metformin reduces intestinal fructose metabolism and glucose production, along with decreased fructose delivery to the liver in mice.

bioRxiv · Apr 17, 2023 · PreprintPhysiology

HGFAC is a ChREBP Regulated Hepatokine that Enhances Glucose and Lipid Homeostasis

A. Sargsyan, L. Doridot, S. A. Hannou, W. Tong, H. Srinivasan, R. Ivison, R. Monn, H. H. Kou, J. M. Haldeman, M. Arlotto, P. J. White, P. A. Grimsrud, I. Astapova, L. Tsai, M. A. Herman

The paper identifies HGFAC as a ChREBP-regulated hepatokine that improves glucose and lipid homeostasis through activation of PPARγ in mice.

bioRxiv · Jul 29, 2021Physiology

Deglutarylation of GCDH by SIRT5 controls lysine metabolism in mice

D. P. Bhatt, C. A. Mills, K. A. Anderson, B. J. Henriques, T. G. Lucas, S. Francisco, J. Liu, O. R. Ilkayeva, A. E. Adams, S. R. Kulkarni, D. S. Backos, P. A. Grimsrud, C. M. Gomes, M. D. Hirschey

This study identifies glutarylation of GCDH by glutaryl-CoA and shows SIRT5 deglutarylates GCDH, restoring its function and regulating lysine metabolism in mice.

bioRxiv · Jun 28, 2020 · PreprintBiochemistry