Author

I. Kondova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Bioengineering· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

B. E. Verstrepen· 2 shared E. J. Verschoor· 2 shared G. Koopman· 2 shared J. A. M. Langermans· 2 shared K. P. Boszormenyi· 2 shared M. A. Stammes· 2 shared P. Mooij· 2 shared A. Brulport· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

B. E. Verstrepen

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Author profile →

6 papers

Recent·Most cited

Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity

A. Brulport, M. A. Gazda, E. Liorzou, M. Daunesse, B. Raquillet, A. Lepelletier, M. Sopena-Rios, P. Regnard, L. Fellmann, L. Faccin, S. Garbit, A. Cermolacce, I. Kondova, M. Raliou, L. Marcellin, , C. Berthelot

The paper compares gene expression in endometrial epithelial cells across humans, mice, and non-human primates to show convergent evolution of uterine receptivity genes like LIF.

bioRxiv · Mar 13, 2024 · PreprintEvolutionary Biology

The molecular evolution of spermatogenesis across mammals

F. Murat, N. Mbengue, S. B. Winge, T. Trefzer, E. Leushkin, M. Sepp, M. Cardoso-Moreira, J. Schmidt, C. Schneider, K. Mössinger, T. Brüning, F. Lamanna, M. R. Belles, C. Conrad, I. Kondova, , H. Kaessmann

This study analyzes single-nucleus transcriptomes from testes across eleven mammalian species to uncover molecular evolution patterns in spermatogenesis.

bioRxiv · Nov 8, 2021Evolutionary Biology

Immunogenicity and protective efficacy of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques

L. Solforosi, H. Kuipers, S. K. Rosendahl Huber, J. E. M. van der Lubbe, L. Dekking, D. N. Czapska-Casey, A. Izquierdo Gil, M. Baert, J. Drijver, J. Vaneman, E. van Huizen, Y. Choi, J. Vreugdenhil, S. Kroos, A. H. de Wilde, , R. C. Zahn

This study evaluates one- and two-dose regimens of the Ad26.COV2.S vaccine in rhesus macaques, showing higher antibody responses with two doses and protection against SARS-CoV-2 in aged animals.

bioRxiv · Nov 17, 2020Immunology

The post-acute phase of SARS-CoV-2 infection in two macaques species is associated with signs of ongoing virus replication and pathology in pulmonary and extrapulmonary tissues

K. P. Boszormenyi, M. A. Stammes, Z. C. Fagrouch, G. Kiemenyi-Kayere, H. Niphuis, D. Mortier, N. van Driel, I. Nieuwenhuis, R. Vervenne, T. Haaksma, B. Ouwerling, D. Adema, R. F. Acar, E. Zuiderwijk-Sick, L. Meijer, , B. E. Verstrepen

This study shows that SARS-CoV-2 persists in multiple tissues and replicates in macaques during the post-acute phase, even after viral RNA is no longer detectable in nasal swabs.

bioRxiv · Nov 5, 2020Microbiology

Ingestible Osmotic Pill for In-vivo Sampling of Gut Microbiome

H. Rezaei Nejad, B. C. M. Oliveira, A. Sadeqi, A. Dehkharghani, I. Kondova, J. A. M. Langermans, J. S. Guasto, S. Tzipori, G. Widmer, S. R. Sonkusale

This paper introduces an ingestible osmotic pill for in vivo gut microbiome sampling and shows it accurately captures bacterial populations from different gut regions.

bioRxiv · Jul 3, 2019 · PreprintBioengineering

Gene expression variability across cells and species shapes innate immunity

T. Hagai, X. Chen, R. J. Miragaia, T. Gomes, R. Rostom, N. Kunowska, V. Proserpio, G. Donati, L. Bossini-Castillo, G. Naamati, G. Emerton, G. Trynka, I. Kondova, M. Denis, S. A. Teichmann

The paper examines how gene expression variability across cells and species influences innate immune responses, finding that rapidly diverging genes show high variability while regulatory genes are conserved.

bioRxiv · Sep 24, 2017Evolutionary Biology