L. du Merle

Transcriptome profiling of human colonic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.

This study profiles the transcriptome of human colonic cells exposed to SGG, showing it induces stronger transcriptional changes in cancerous HT29 cells than in normal FHC cells, with significant ER stress and UPR activation.

Gallocin A, an atypical two-peptide bacteriocin with intramolecular disulfide bonds required for activity

This paper characterizes gallocin A, a two-peptide bacteriocin from SGG, showing it requires intramolecular disulfide bonds for activity and that its immunity peptide shares structural features with the toxin.

Bacteriocin production in Streptococcus gallolyticus by a complex 4-component regulatory system with activator and anti-activator activities

This paper identifies a 4-component regulatory system in Streptococcus gallolyticus that controls gallocin production through activator and anti-activator proteins.

Heterogeneous expression of Pil3 pilus is critical for Streptococcus gallolyticus translocation across polarized colonic epithelial monolayers

This paper shows that heterogeneous Pil3 pilus expression in Streptococcus gallolyticus enables translocation across intestinal epithelial barriers.