Author

P. Trieu-Cuot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 10

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2

Frequent Co-Authors

S. Dramsi· 5 shared L. du Merle· 4 shared O. Sismeiro· 4 shared R. Legendre· 4 shared A. Firon· 3 shared H. Varet· 3 shared A. Gruss· 2 shared A. Pathania· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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5 shared papersMicrobiology

S. Dramsi

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10 papers

Recent·Most cited

Coordinated regulation of osmotic imbalance by c-di-AMP shapes beta-lactam tolerance in Group B Streptococcus

T. Brissac, C. Guyonnet, A. Sadouni, A. Hernandez Montoya, E. Jacquemet, R. Legendre, O. Sismeiro, P. Trieu-Cuot, P. Lanotte, A. Tazi, A. Firon

This study identifies c-di-AMP's role in beta-lactam tolerance in Group B Streptococcus by coordinating osmotic regulation and cell envelope stress responses.

bioRxiv · Mar 27, 2024 · PreprintMicrobiology

Signal-independent activation reveals two-component regulatory networks

C. Claverie, F. Coppolino, M.-V. Mazzuoli, C. Guyonnet, E. Jacquemet, R. Legendre, O. Sismeiro, G. V. De Gaetano, G. Teti, P. Trieu-Cuot, A. Tazi, C. Beninati, A. Firon

This study identifies two-component regulatory networks in Streptococcus agalactiae by activating histidine kinases to reveal connections between regulatory systems and their roles in pathogenicity and cell envelope homeostasis.

bioRxiv · Mar 22, 2024 · PreprintMicrobiology

Transcriptome profiling of human colonic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.

E. Pasquereau-Kotula, L. du Merle, O. Sismeiro, N. Pietrosemoli, H. Varet, R. Legendre, P. Trieu-Cuot, S. Dramsi

This study profiles the transcriptome of human colonic cells exposed to SGG, showing it induces stronger transcriptional changes in cancerous HT29 cells than in normal FHC cells, with significant ER stress and UPR activation.

bioRxiv · May 16, 2023 · PreprintMicrobiology

Gallocin A, an atypical two-peptide bacteriocin with intramolecular disulfide bonds required for activity

A. Proutiere, L. du Merle, M. Garcia-Lopez, C. Leger, A. Voegele, A. Chenal, A. Harrington, Y. Tal-Gan, T. Cokelaer, P. Trieu-Cuot, S. Dramsi

This paper characterizes gallocin A, a two-peptide bacteriocin from SGG, showing it requires intramolecular disulfide bonds for activity and that its immunity peptide shares structural features with the toxin.

Microbiology Spectrum · Apr 13, 2023Peer-reviewedMicrobiology

The oncogenic role of Streptococcus gallolyticus subsp. gallolyticus is linked to activation of multiple cancer-related signaling pathways

E. Pasquereau-Kotula, G. Nigro, F. Dingli, D. Loew, P. Poullet, Y. Xu, S. Kopetz, J. Davis, L. Peduto, C. Robbe-Masselot, P. Sansonetti, P. Trieu-Cuot, S. Dramsi

This study shows that SGG UCN34 promotes colon cancer by activating multiple cancer-related signaling pathways through proteomic and phosphoproteomic analyses in mice and human tumors.

bioRxiv · Feb 17, 2023 · PreprintMicrobiology

Prophages divert Staphylococcus aureus defenses against host lipids

B. Zhou, A. Pathania, D. Pant, D. Halpern, P. Gaudu, P. Trieu-Cuot, A. Dias-Leao, C. Pagot, A. Solgadi, A. Gruss, K. Gloux

This study shows that prophages in Staphylococcus aureus modulate lipid incorporation into bacterial membranes, affecting antibiotic resistance and infection dynamics.

bioRxiv · Jan 27, 2022 · PreprintMicrobiology

(p)ppGpp/GTP and malonyl-CoA modulate Staphylococcus aureus adaptation to FASII antibiotics and provide a basis for synergistic bi-therapy

A. Pathania, J. Anba-Mondoloni, M. Gominet, D. Halpern, J. Dairou, L. Dupont, G. Lamberet, P. Trieu-Cuot, K. Gloux, A. Gruss

This paper shows that (p)ppGpp and malonyl-CoA modulate S. aureus adaptation to FASII antibiotics, and that combining a (p)ppGpp inducer with an anti-FASII drug blocks bacterial outgrowth.

mBio · Feb 23, 2021Peer-reviewedMicrobiology

The CovR regulatory network drives the evolution of Group B Streptococcus virulence

M. V. Mazzuoli, M. Daunesse, H. Varet, I. Rosinski-Chupin, R. Legendre, O. Sismeiro, M. Gominet, P. A. Kaminski, P. Glaser, C. Chica, P. Trieu-Cuot, A. Firon

This study characterizes the CovR regulatory network in Group B Streptococcus, showing its role in virulence gene regulation and strain-specific adaptations.

bioRxiv · Jan 25, 2021Microbiology

Bacteriocin production in Streptococcus gallolyticus by a complex 4-component regulatory system with activator and anti-activator activities

A. Proutiere, B. Perichon, L. du Merle, H. Varet, P. Trieu-Cuot, S. Dramsi

This paper identifies a 4-component regulatory system in Streptococcus gallolyticus that controls gallocin production through activator and anti-activator proteins.

bioRxiv · Jun 4, 2020Microbiology

Heterogeneous expression of Pil3 pilus is critical for Streptococcus gallolyticus translocation across polarized colonic epithelial monolayers

S. Dramsi, M. Martins, L. du Merle, P. Trieu-Cuot

This paper shows that heterogeneous Pil3 pilus expression in Streptococcus gallolyticus enables translocation across intestinal epithelial barriers.

bioRxiv · Jun 25, 2019Microbiology