Author

L. E. Crotty Alexander

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Das· 2 shared A. Claire· 1 shared A. Fonseca· 1 shared A. Jahan· 1 shared A. Marson· 1 shared A. Moshensky· 1 shared A. R. Atkins· 1 shared A. Sharma· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

S. Das

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivMar 9, 2021

Effect of chronic JUUL aerosol inhalation on inflammatory states of the brain, lung, heart and colon in mice

A. Moshensky, C. Brand, H. Alhaddad…·L. E. Crotty Alexander

Chronic JUUL aerosol inhalation in mice alters inflammatory states in brain, lung, heart, and colon, with flavor-dependent effects and potential long-term health risks.

DOI 10.7554/elife.67621

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivOct 17, 2020

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19

C. Tindle, M. Fuller, A. Fonseca…·S. Das

This study develops a human lung organoid model to emulate COVID-19 pathogenesis, showing proximal airway cells drive viral infection while distal cells drive excessive immune response.

DOI 10.7554/elife.66417

humanorganoid / primary culture

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 31, 2019

Obesity Potentiates TH2 Immunopathology via Dysregulation of PPAR

S. Bapat, Y. Liang, S. Liu…·Y. Zheng

This study shows obesity increases TH2 immunopathology by disrupting PPARγ in T cells, and TZDs can protect against this effect in obese mice.

DOI 10.1101/825836

mouseproteomics

𝕏 PostBluesky