Author

L. E. Dunnett

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Biophysics· 1

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Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Douangamath· 1 shared D. A. Keedy· 1 shared D. Axford· 1 shared E. R. Nelson· 1 shared F. von DelftiD· 1 shared H. Orins· 1 shared J. T. Biel· 1 shared N. G. Paterson· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

A. Douangamath

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1 paper

Recent·Most cited

Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B

T. S. Mehlman, J. T. Biel, S. M. Azeem, E. R. Nelson, S. Hossain, L. E. Dunnett, N. G. Paterson, A. Douangamath, R. Talon, D. Axford, H. Orins, F. von Delft, D. A. Keedy

This study compares cryo and room-temperature crystallography of PTP1B with small-molecule fragments, showing RT reveals different binding modes and conformational changes.

bioRxiv · Nov 2, 2022Biophysics