Author

L. E. Lucca

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. A. Hafler· 2 shared K. Raddassi· 2 shared P.-P. Axisa· 2 shared A. Perrot· 1 shared B. A. Lerner· 1 shared B. Harnett· 1 shared B. Lu· 1 shared B. Rigaud· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

D. A. Hafler

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Author profile →

3 papers

Recent·Most cited

Inflamed Natural Killer cells with adhesion defects are associated with a poor prognosis in Multiple Myeloma

E. Blanquart, R. Ekren, B. Rigaud, M.-V. Joubert, V. Baylot, H. Daunes, M. Cuisinier, M. Villard, N. Carrie, C. Mazzotti, L. E. Lucca, A. Perrot, J. Corre, T. Walzer, H. Avet-Loiseau, , L. Martinet

This study identifies CD16/CD226low NK cells with inflammatory signatures and reduced effector functions in multiple myeloma patients, correlating with poor clinical outcomes.

bioRxiv · Jan 15, 2024 · PreprintImmunology

Circulating Clonally Expanded T Cells Reflect Functions of Tumor Infiltrating T Cells

L. E. Lucca, P.-P. Axisa, B. Lu, B. Harnett, S. Jessel, L. Zhang, K. Raddassi, L. Zhang, K. Olino, J. Clune, M. Singer, H. Kluger, D. A. Hafler

The paper examines circulating T cells sharing TCRs with tumor-infiltrating T cells in metastatic melanoma patients, finding they exhibit effector gene signatures similar to tumor T cells.

Journal of Experimental Medicine · Mar 2, 2021Peer-reviewedImmunology

Differential expression of the T cell inhibitor TIGIT in Glioblastoma and Multiple Sclerosis

L. E. Lucca, B. A. Lerner, D. DeBartolo, C. Park, G. Ponath, K. Raddassi, D. A. Hafler, D. Pitt

The paper compares TIGIT expression in glioblastoma tumor-infiltrating T cells and multiple sclerosis lesions, finding higher TIGIT expression in GBM and suggesting anti-TIGIT therapy as a potential treatment.

bioRxiv · Mar 27, 2019 · PreprintImmunology