Author

L. F. A. Wessels

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. A. Singh· 1 shared A. Broeks· 1 shared A. Duarte· 1 shared A. Gil-Jimenez· 1 shared A. Kojic· 1 shared B. Morris· 1 shared B. van den Broek· 1 shared B. van Rhijn· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCancer Biology

A. A. Singh

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Author profile →

4 papers

Recent·Most cited

Cancer BiologybioRxivJul 25, 2023

Enhancer plasticity in endometrial tumorigenesis demarcates non-coding somatic mutations and 3D-genome alterations boosting the oncogenic driver ESR1

S. Gregoricchio, A. Kojic, M. Hoogstraat…·W. Zwart

The paper identifies enhancer plasticity and 3D-genome alterations in endometrial cancer that boost ESR1 expression through non-coding mutations and risk variants.

DOI 10.1186/s13059-025-03596-5

humanHi-C

𝕏 PostBluesky

Cancer BiologybioRxivMay 25, 2023

Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors

A. Gil-Jimenez, N. van Dijk, J. L. Vos…·L. F. A. Wessels

DOI 10.1038/s41467-024-46450-1

humanimaging

𝕏 PostBluesky

Cancer BiologybioRxivSep 7, 2022

Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors

J. Bhin, M. Paes Dias, E. Gogola…·J. Jonkers

DOI 10.1016/j.celrep.2023.112538

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 14, 2021

γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects

N. L. de Vries, J. v. d. Haar, V. Veninga…·E. E. Voest

This study shows that γδ T cells, not CD8+ T cells, mediate immune checkpoint blockade efficacy in HLA class I-negative, MMR-d colon cancers.

DOI 10.1101/2021.10.14.464229

humanproteomics

𝕏 PostBluesky