Author

M. Hoogstraat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:Hi-C· 1

Frequent Co-Authors

S. Stelloo· 2 shared W. Zwart· 2 shared A. A. Singh· 1 shared A. Kojic· 1 shared A. M. Bergman· 1 shared B. Gokbayrak· 1 shared B. McConeghy· 1 shared C. Collins· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

S. Stelloo

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Author profile →

2 papers

Recent·Most cited

Enhancer plasticity in endometrial tumorigenesis demarcates non-coding somatic mutations and 3D-genome alterations boosting the oncogenic driver ESR1

S. Gregoricchio, A. Kojic, M. Hoogstraat, K. Schuurman, S. Stelloo, T. M. Severson, T. A. O'Mara, M. Droog, A. A. Singh, D. M. Glubb, L. F. A. Wessels, M. Vermeulen, F. van Leeuwen, W. Zwart

The paper identifies enhancer plasticity and 3D-genome alterations in endometrial cancer that boost ESR1 expression through non-coding mutations and risk variants.

bioRxiv · Jul 25, 2023Cancer Biology

Functional mapping of androgen receptor enhancer activity

C.-C. F. Huang, S. Lingadahalli, T. Morova, D. Ozturan, E. Hu, I. P. L. Yu, S. Linder, M. Hoogstraat, S. Stelloo, F. Sar, H. van der Poel, U. B. Altintas, M. Saffarzadeh, S. Le Bihan, B. McConeghy, , N. A. Lack

The paper functionally maps AR enhancer activity using STARRseq, finding most AR binding sites are inactive or constitutively active, with inducible enhancers forming regulatory hubs that drive gene transcription.

bioRxiv · Aug 18, 2020Cancer Biology