Author

L. Fernandez-Cuesta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

M. Foll· 3 shared N. Alcala· 3 shared A. Sexton-Oates· 2 shared C. Voegele· 2 shared H. Clevers· 2 shared L. Mangiante· 2 shared T. L. Dayton· 2 shared A. F. M. Dost· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

M. Foll

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3 papers

Recent·Most cited

Multi-omic dataset of patient-derived tumor organoids of neuroendocrine neoplasms

N. Alcala, C. Voegele, L. Mangiante, A. Sexton-Oates, H. Clevers, L. Fernandez-Cuesta, T. L. Dayton, M. Foll

The paper presents a multi-omic dataset of patient-derived tumor organoids for neuroendocrine neoplasms, including whole-genome and RNA-seq data, and provides analysis tools for re-use.

bioRxiv · Aug 31, 2023Cancer Biology

Druggable Growth Dependencies and Tumor Evolution Analysis in Patient-Derived Organoids of Neuroendocrine Cancer

T. L. Dayton, N. Alcala, L. Moonen, L. den Hartigh, L. Mangiante, L. Lap, A. F. M. Dost, J. Beumer, S. Levy, R. S. van Leeuwaarde, W. M. Hackeng, K. Samsom, C. Voegele, A. Sexton-Oates, H. Begthel, , H. Clevers

This study establishes patient-derived tumor organoids (PDTOs) for neuroendocrine cancers, identifies therapeutic vulnerabilities, and highlights EGF dependency in pulmonary neuroendocrine tumors.

bioRxiv · Oct 31, 2022Cancer Biology

Redefining mesothelioma types as a continuum uncovers the immune and vascular systems as key players in the diagnosis and prognosis of this disease

N. Alcala, C. Caux, N. Girard, J. D. D. McKay, F. Galateau-Salle, M. Foll, L. Fernandez-Cuesta

This study redefines mesothelioma as a continuum rather than distinct types, identifying immune and vascular pathways as key factors in prognosis and potential therapeutic targets.

bioRxiv · May 30, 2018Cancer Biology