N. Girard

Ex vivo quantification of anti-tumor T-cell activity upon anti-PD-1 treatment in patient-derived lung tumor-on-chip

This study develops and validates lung-tumor-on-chip platforms to measure ex vivo anti-PD-1 treatment effects on T-cell activity using live imaging and image analysis.

Unravelling the puzzle of anthranoids metabolism in living plant cells using spectral imaging coupled to mass spectrometry

The paper develops a strategy combining spectral imaging, confocal microscopy, and mass spectrometry to study anthranoid metabolism in plant cells and identify their fluorescent properties and metabolic transformations.

Contribution of resident and circulating precursors to tumor-infiltrating CD8+ T cell populations in non-small cell lung cancer patients

The paper identifies two CD8+ TIL subpopulations in NSCLC, one circulating and one resident, which transition into terminally differentiated cells through a unique state.

Redefining mesothelioma types as a continuum uncovers the immune and vascular systems as key players in the diagnosis and prognosis of this disease

This study redefines mesothelioma as a continuum rather than distinct types, identifying immune and vascular pathways as key factors in prognosis and potential therapeutic targets.

Activation of the mTOR/ Akt pathway in thymic epithelial cells derived from thymomas

This study examines the activation of the Akt/mTOR pathway in thymic epithelial cells from thymomas and shows that mTOR inhibitors reduce cell proliferation.