M. Foll

Multi-omic dataset of patient-derived tumor organoids of neuroendocrine neoplasms

The paper presents a multi-omic dataset of patient-derived tumor organoids for neuroendocrine neoplasms, including whole-genome and RNA-seq data, and provides analysis tools for re-use.

Druggable Growth Dependencies and Tumor Evolution Analysis in Patient-Derived Organoids of Neuroendocrine Cancer

This study establishes patient-derived tumor organoids (PDTOs) for neuroendocrine cancers, identifies therapeutic vulnerabilities, and highlights EGF dependency in pulmonary neuroendocrine tumors.

The fitness consequences of genetic variation in wild populations of mice

The paper investigates how genetic variation in wild mice affects fitness by linking genotype to phenotype and allele frequency changes through field and lab experiments.

Redefining mesothelioma types as a continuum uncovers the immune and vascular systems as key players in the diagnosis and prognosis of this disease

This study redefines mesothelioma as a continuum rather than distinct types, identifying immune and vascular pathways as key factors in prognosis and potential therapeutic targets.

The evolutionary history of Nebraska deer mice: local adaptation in the face of strong gene flow

This study examines the demographic and selective history of deer mice in Nebraska, finding that gene flow homogenizes most of the genome but the Agouti locus shows local adaptation due to cryptic coloration.