Centriole growth is not limited by a finite pool of components, but is limited by the Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL
T. L. Steinacker, S.-S. Wong, Z. A. Novak, S. Saurya, L. Gartenmann, E. J. H. van Houtum, J. R. Sayers, B. C. Lagerholm, J. W. Raff
The paper shows that centriole growth in Drosophila embryos is not limited by component availability but by Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL, which regulates growth timing.
bioRxiv · Feb 15, 2022Cell Biology