Author

L. Gelens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Organism:Xenopus· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. A. Martinez· 1 shared A. D. Garg· 1 shared A. Liston· 1 shared B. J. Van den Eynde· 1 shared D. Gonze· 1 shared D. Lambrechts· 1 shared D. M. Borras· 1 shared D. Ruiz-Reynes· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

A. A. Martinez

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mitotic waves in frog egg extracts: Transition from phase waves to trigger waves

O. Puls, D. Ruiz-Reynes, F. Tavella, M. Jin, Y. Kim, L. Gelens, Q. Yang

The paper observes a transition from phase waves to trigger waves in Xenopus egg extracts and shows how these waves coordinate the cell cycle over long distances.

bioRxiv · Jan 18, 2024 · PreprintBiophysics

Immunogenomic, single-cell and spatial dissection of CD8+T cell exhaustion reveals critical determinants of cancer immunotherapy

S. Naulaerts, D. M. Borras, A. A. Martinez, J. Messiaen, Y. Van Herck, L. Gelens, T. Venken, I. Vanmeerbeek, S. More, J. Sprooten, O. Bechter, G. Bergers, A. Liston, S. De Vleeschouwer, B. J. Van den Eynde, , A. D. Garg

This study identifies distinct CD8+T cell states in cancer patients using multi-omics data, showing that dysfunctional states resist immunotherapy while exhausted states can be targeted with specific treatments.

bioRxiv · Nov 22, 2021Immunology

Bistable, biphasic regulation of PP2A-B55 accounts for the dynamics of mitotic substrate phosphorylation

J. Kamenz, L. Gelens, J. E. Ferrell

The paper shows PP2A-B55 acts as a bistable switch and is regulated biphasically by Cdk1, influencing mitotic substrate phosphorylation dynamics.

Current Biology · Feb 1, 2021Peer-reviewedCell Biology

Mutualistic cross-feeding in microbial systems generates bistability via an Allee effect

D. Gonze, L. Gelens, S. Vet

The paper shows that mutualistic cross-feeding in microbial systems can lead to bistability via an Allee effect, influenced by dilution rates and nutrient dynamics.

bioRxiv · Dec 23, 2019Ecology