Author

L. H. Moncla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Approach:experimental assay· 1 Organism:rat· 1 Research Focus:variant calling· 1

Frequent Co-Authors

T. Bedford· 3 shared C. Wagner· 1 shared D. A. Baker· 1 shared D. O'Connor· 1 shared E. A. Karlsson· 1 shared G. K. Moreno· 1 shared H. Zhu· 1 shared J. D. Bloom· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

T. Bedford

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Limited within-host diversity and tight transmission bottlenecks limit SARS-CoV-2 evolution in acutely infected individuals

K. Braun, G. K. Moreno, C. Wagner, M. A. Accola, W. M. Rehrauer, D. A. Baker, K. Koelle, D. O'Connor, T. Bedford, T. Friedrich, L. H. Moncla

The paper analyzes SARS-CoV-2 within-host diversity and transmission bottlenecks in acute infections, finding limited diversity and narrow bottlenecks that restrict variant spread.

bioRxiv · Apr 30, 2021 · PreprintEvolutionary Biology

Quantifying within-host diversity of H5N1 influenza viruses in humans and poultry in Cambodia

L. H. Moncla, T. Bedford, P. Dussart, S. V. Horm, S. Rith, P. Buchy, E. A. Karlsson, L. Li, Y. Liu, H. Zhu, Y. Guan, T. C. Friedrich, P. F. Horwood

The paper analyzes H5N1 influenza virus evolution in humans and ducks in Cambodia, finding human-adapting mutations but limited within-host evolution due to selection pressures.

PLOS Pathogens · Jan 17, 2020Peer-reviewedMicrobiology

Comprehensive mapping of avian influenza polymerase adaptation to the human host

Y. Q. S. Soh, L. H. Moncla, R. Eguia, T. Bedford, J. D. Bloom

This study maps amino-acid mutations in avian influenza PB2 polymerase that enhance growth in human cells, identifying new adaptive mutations and their evolutionary constraints.

bioRxiv · Jan 4, 2019Microbiology