Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis
N. Kiweler, C. Delbrouck, V. I. Pozdeev, L. Neises, L. Soriano-Baguet, K. Eiden, F. Xian, M. Benzarti, L. Haase, E. Koncina, M. Schmoetten, C. Jaeger, M. Z. Noman, A. Vazquez, B. Janji, , J. Meiser
This study identifies mitochondrial one-carbon metabolism as a key driver of cancer cell migration and metastasis independent of proliferation.
Nature Communications · May 16, 2022Peer-reviewedCancer Biology