Author

M. Benzarti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Jaeger· 2 shared E. Letellier· 2 shared J. Meiser· 2 shared L. Neises· 2 shared M. Schmoetten· 2 shared A. Lesur· 1 shared A. Oudin· 1 shared A. Vazquez· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

C. Jaeger

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2 papers

Recent·Most cited

PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle

M. Benzarti, A. Oudin, E. Viry, E. Gargiulo, M. Schmoetten, L. Neises, C. Pulido, N. I. Lorenz, M. W. Ronellenfitsch, D. Sumpton, M. Warmoes, C. Jaeger, A. Lesur, J. Paggetti, E. Moussay, , J. Meiser

This study reveals that PKM2 inhibition redirects glycolytic and glutamine carbons into distinct metabolic pathways, supporting cancer cell metabolic flexibility under glycolytic limitation.

bioRxiv · Jan 23, 2023Cancer Biology

Mitochondria preserve an autarkic one-carbon cycle to confer growth-independent cancer cell migration and metastasis

N. Kiweler, C. Delbrouck, V. I. Pozdeev, L. Neises, L. Soriano-Baguet, K. Eiden, F. Xian, M. Benzarti, L. Haase, E. Koncina, M. Schmoetten, C. Jaeger, M. Z. Noman, A. Vazquez, B. Janji, , J. Meiser

This study identifies mitochondrial one-carbon metabolism as a key driver of cancer cell migration and metastasis independent of proliferation.

Nature Communications · May 16, 2022Peer-reviewedCancer Biology