Five inhibitory receptors display distinct vesicular distributions in T cells
J. Lu, A. Veler, B. Simonetti, T. Raj, P. H. Chou, S. J. Cross, A. M. Phillips, X. Ruan, L. Huynh, A. W. Dowsey, D. Ye, R. F. Murphy, P. Verkade, P. J. Cullen, C. Wuelfing
The paper characterizes the subcellular distributions of five inhibitory receptors in T cells and finds they are distinct, with CTLA-4 preferentially associating with lysosomal-derived vesicles.
bioRxiv · Jul 21, 2023Immunology