Author

L. Josa-Cullere

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

P. Vyas· 2 shared T. R. Jackson· 2 shared A. J. Russell· 1 shared A. O'Mahony· 1 shared A. Russell· 1 shared A. Vuorinen· 1 shared C. J. R. Bataille· 1 shared D. Conole· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

P. Vyas

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

HDAC inhibitor derivatives induce differentiation of leukemic cells through two distinct and separable mechanisms

P. Kumar, L. Josa-Cullere, T. R. Jackson, C. J. R. Bataille, P. Vyas, T. A. Milne, A. J. Russell

The paper shows HDAC inhibitors induce AML cell differentiation via two distinct mechanisms: one through G1 arrest and another through G2 arrest via Aurora A and GSK3 inhibition.

bioRxiv · Jan 6, 2024 · PreprintPharmacology & Toxicology

A novel tubulin binding molecule drives differentiation of acute myeloid leukaemia cells

T. R. Jackson, A. Vuorinen, L. Josa-Cullere, K. S. Madden, D. Conole, T. J. Cogswell, I. V. L. Wilkinson, L. M. Kettyle, D. Zhang, A. O'Mahony, D. Gracias, L. McCall, R. Westwood, G. C. Terstappen, S. G. Davies, , T. Milne

The paper identifies a novel tubulin-binding molecule that induces differentiation in AML cells, reducing tumour burden and improving survival in vivo.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology