L. K. Davis

Sex differences in immune function and disease risk are not easily explained by an evolutionary mismatch

This study examines sex differences in immune function and disease risk across populations, finding no consistent support for the evolutionary mismatch hypothesis.

Biophysical basis of phage liquid crystalline droplet-mediated antibiotic tolerance in pathogenic bacteria

This study investigates liquid crystalline droplets formed by inoviral phages in bacteria, showing they protect cells from antibiotics through biophysical properties rather than surface chemistry.

Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies

This study uses a physical model to predict how different nuclear transport receptors (NTRs) modulate each other's penetration through FG nucleoporin assemblies, revealing phase separation at physiologically relevant concentrations.

A Comprehensive Analysis of Allostery in 14-3-3 ζ Docking Proteins using the Spatial Convolution Model (SCM)

This paper uses the Spatial Convolution Model (SCM) to analyze allostery in 14-3-3 ζ docking proteins by modeling wave propagation and entropy transfer across three scales.

Physical modelling of multivalent interactions in the nuclear pore complex

This study develops computational models to analyze the role of heterogeneity in FG Nups and NTRs, finding minor effects on binding equilibria but significant impacts on kinetics and multivalency.

Modelling fibrillogenesis of collagen-mimetic molecules

This paper develops a computational model to study how charged residues on collagen-mimetic molecules drive the formation of striped fibrils, showing that multi-body interactions determine the fibril pattern.

Intrinsically disordered nuclear pore proteins show ideal-polymer morphologies and dynamics

This study shows FG nups in the nuclear pore complex exhibit ideal-polymer behavior, balancing repulsive and attractive interactions to enable both cohesion and dynamic transport.

Dancing Molecules: Rewiring Cooperative Communications within 14-3-3 ζ Docking Proteins

The paper rewires cooperative communications in 14-3-3 ζ docking protein using the Fundamental Theory of the Evolution Force to increase flexibility and discover evolutionary blueprints encoded in the genome.