Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM1
M. L. B. Grönloh, J. J. G. Arts, S. Palacios Martinez, A. A. van der Veen, L. Kempers, A. C. I. van Steen, J. J. T. H. Roelofs, M. A. Nolte, J. Goedhart, J. D. van Buul
The paper identifies endothelial transmigration hotspots that limit vascular leakage by heterogeneous ICAM-1 expression, showing that ICAM-1 distribution determines hotspot location and function.
bioRxiv · Jan 14, 2022 · PreprintImmunology