Author

L. Kisiswa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Andersson· 1 shared A. Nykjaer· 1 shared A. Ramanujan· 1 shared C. F. Ibanez· 1 shared D. Fernandez-Suarez· 1 shared D. I. Park· 1 shared E. Sim· 1 shared E. W. Sim· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Andersson

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2 papers

Recent·Most cited

AraC binds the p75NTR transmembrane domain to induce neurodegeneration in mature neurons.

V. S. Lopes Rodrigues, P. Boxy, E. Sim, D. I. Park, A. Andersson, D. Fernandez-Suarez, J. Carbonell, A. Nykjaer, L. Kisiswa

This study shows AraC binds p75NTR's transmembrane domain, causing neurodegeneration in mature neurons by disrupting NFκB signaling and activating JNK-mediated cell death.

bioRxiv · Dec 1, 2021 · PreprintCell Biology

Structural and functional elucidation of NF-κB signaling by the p75 neurotrophin receptor through recruitment of TRADD

N. Zhang, L. Kisiswa, A. Ramanujan, Z. Li, E. W. Sim, W. Yuan, C. F. Ibanez, Z. LIN

This study determines the structure of the p75NTR-DD/TRADD-DD complex and shows TRADD recruitment regulates NF-κB signaling and cell survival in cerebellar granule neurons.

bioRxiv · Feb 7, 2021 · PreprintBiophysics