Cellular Stress Signaling Activates Type-I IFN Response Through FOXO3-regulated Lamin Posttranslational Modification
I. Hwang, Z. Dai, F. Li, T. Sanchez, J. W. Locasale, L. L. Cantley, H. Zheng, J. Paik
The paper shows that oxidative stress in NSPCs activates the IFN-I response via FOXO3-regulated lamin modifications, preserving their regenerative potential.
bioRxiv · May 3, 2020Cell Biology