Author

L. L. He

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

P. Ma· 2 shared R. P. Bhattacharyya· 2 shared A. Earl· 1 shared A. L. Manson· 1 shared A. Pironti· 1 shared C. M. Ernst· 1 shared C. S. Smillie· 1 shared D. Hung· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

P. Ma

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Bacterial droplet-based single-cell RNA-seq reveals heterogeneity in bacterial populations and in response to antibiotic perturbation

P. Ma, H. M. Amemiya, L. L. He, S. J. Gandhi, R. Nicol, R. P. Bhattacharyya, C. S. Smillie, D. T. Hung

BacDrop enables single-cell RNA-seq of bacteria, revealing population heterogeneity and differential responses to antibiotics in Klebsiella pneumoniae.

bioRxiv · Aug 1, 2022 · PreprintMicrobiology

Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics

D. Hung, P. Ma, L. L. He, A. Pironti, H. H. Laibinis, C. M. Ernst, A. L. Manson, R. P. Bhattacharyya, A. Earl, J. Livny

This study identifies genetic factors that facilitate the evolution of carbapenem resistance in Klebsiella pneumoniae, highlighting transposon mutagenesis and mutation spectra as key contributors to resistance development.

bioRxiv · Feb 11, 2021Evolutionary Biology