Author

C. M. Ernst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Peschel· 2 shared C. J. Slavetinsky· 2 shared J. N. Hauser· 2 shared A. Earl· 1 shared A. Geyer· 1 shared A. Kengmo Tchoupa· 1 shared A. Kraus· 1 shared A. L. Manson· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

A. Peschel

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PplT domain proteins - ubiquitous potential prokaryotic phospholipid translocases

J. N. Hauser, A. Kengmo Tchoupa, S. Zabel, K. Nieselt, C. M. Ernst, C. J. Slavetinsky, A. Peschel

The paper identifies PplT domain proteins in bacteria and archaea as potential phospholipid translocases, showing their role in membrane lipid metabolism and growth.

bioRxiv · Mar 11, 2022 · PreprintMicrobiology

Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics

D. Hung, P. Ma, L. L. He, A. Pironti, H. H. Laibinis, C. M. Ernst, A. L. Manson, R. P. Bhattacharyya, A. Earl, J. Livny

This study identifies genetic factors that facilitate the evolution of carbapenem resistance in Klebsiella pneumoniae, highlighting transposon mutagenesis and mutation spectra as key contributors to resistance development.

bioRxiv · Feb 11, 2021Evolutionary Biology

Sensitizing Staphylococcus aureus to antibacterial host defense by decoding and blocking the lipid flippase MprF

C. J. Slavetinsky, J. N. Hauser, C. Gekeler, J. Slavetinsky, A. Geyer, A. Kraus, D. Heilingbrunner, S. Wagner, M. Tesar, B. Krismer, S. Kuhn, C. M. Ernst, A. Peschel

This study develops MprF-targeting monoclonal antibodies that block the lipid flippase MprF, increasing MRSA susceptibility to antimicrobial peptides and antibiotics.

bioRxiv · Nov 12, 2020Microbiology