Author

L. L. Liu

University of California, Riverside

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Brech· 1 shared A. Pfefferle· 1 shared B. Jacobs· 1 shared C. Grimm· 1 shared C. Tian· 1 shared D. Clement· 1 shared D. L. Keefe· 1 shared E. H. Ask· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperImmunology

A. Brech

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3 papers

Recent·Most cited

Duplex Reverse Transcription Loop-Mediated Isothermal Amplification on a Nanofluidic Digital Chip (Nano-dChip)

Natalie Luu, L. L. Liu, Esmeralda Ruiz-Garcia, Juhong Chen, Steve Jeffrey Dollery, Gregory J. Tobin, Ke Du

The paper introduces a nanofluidic digital chip for rapid, low-cost viral RNA detection with high sensitivity and specificity, demonstrating its effectiveness for SARS-CoV-2 and Influenza H3.

bioRxiv · Mar 20, 2026 · PreprintBioengineering

Comprehensive molecular features of polycystic ovary syndrome revealed by transcriptome analysis of oocytes and cumulus cells

J. Li, H. Chen, M. Gou, C. Tian, H. Wang, X. Song, D. L. Keefe, X. Bai, L. L. Liu

This study identifies altered gene expression and cell interactions in oocytes and cumulus cells of PCOS patients, highlighting dysregulated microtubule genes and transposable elements.

bioRxiv · Jan 30, 2021Cell Biology

Modulation of Secretory Lysosomes During NK Cell Education Leads to Accumulation of Granzyme B and Enhanced Functional Potential

J. P. Goodridge, B. Jacobs, M. L. Satersmoen, D. Clement, T. Clancy, E. Skarpen, A. Brech, J. Landskron, C. Grimm, A. Pfefferle, L. Meza-Zepeda, S. Lorenz, M. T. Wiiger, W. E. Louch, E. H. Ask, , K.-J. Malmberg

This study shows that NK cell education leads to accumulation of granzyme B in secretory lysosomes, enhancing cytotoxic function through lysosomal Ca2+ signaling and TRPML1 regulation.

bioRxiv · Jul 4, 2018Immunology