ImmunologyProceedings of the National Academy of SciencesPeer-reviewed
CSF-1 maintains pathogenic but not homeostatic myeloid cells in the central nervous system during autoimmune neuroinflammation.
D. Hwang, L. L. W. Ishiwaka, A. Boehm…·B. Ciric
This study shows that blocking CSF-1 reduces harmful myeloid cells in EAE without affecting beneficial ones, suggesting CSF-1 as a therapeutic target for MS.
DOI 10.1073/pnas.2111804119